DrugID

Leflunomide vs Methotrexate

Compare Leflunomide and Methotrexate side by side: what they treat, drug class, cost and FDA label information.

LeflunomideMethotrexate
Drug classAntirheumatic AgentFolate Analog Metabolic Inhibitor
Used to treatRheumatoid arthritisBreast neoplasms, Choriocarcinoma, Crohn disease, Esophageal neoplasms, Hydatidiform mole, Juvenile arthritis, Leukemia, Lung neoplasms, Mycosis fungoides, Osteosarcoma, Psoriasis, Rheumatoid arthritis, Stomach neoplasms, Testicular neoplasms
Generic priceFrom $0.29 each, about $8.83 for 30 (20 mg tablet)From $0.16 each, about $4.73 for 30 (2.5 mg tablet); other forms from $0.70 per mL (250 mg/10 mL vial)
Brand priceNo brand price listedNo brand price listed
Generic savingsNot listedNot listed