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Hydrochlorothiazide vs Spironolactone

Compare Hydrochlorothiazide and Spironolactone side by side: what they treat, drug class, cost and FDA label information.

HydrochlorothiazideSpironolactone
Drug classThiazide DiureticAldosterone Antagonist
Used to treatEdema, Heart failure, High blood pressure, Nephrotic syndromeAscites, Edema, Heart failure, High blood pressure, Hirsutism, Hyperaldosteronism, Hypokalemia
Generic priceFrom $0.012 each, about $0.35 for 30 (25 mg tablet)From $0.043 each, about $1.28 for 30 (25 mg tablet); other forms from $1.81 per mL (25 mg/5 mL suspension)
Brand priceNo brand price listedNo brand price listed
Generic savingsNot listedNot listed