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Diphenhydramine vs Fexofenadine

Compare Diphenhydramine and Fexofenadine side by side: what they treat, drug class, cost and FDA label information.

DiphenhydramineFexofenadine
Drug classHistamine-1 Receptor AntagonistHistamine-1 Receptor Antagonist
Used to treatAnxiety, Insomnia, Motion sickness, Nausea, Rhinitis, allergic, perennial, Sneezing, UrticariaRhinitis, allergic, perennial, Urticaria
Generic priceFrom $0.030 each, about $0.89 for 30 (50 mg capsule); other forms from $0.017 per mL (12.5 mg/5 mL)From $0.15 each, about $4.59 for 30 (60 mg tablet)
Brand priceNo brand price listedNo brand price listed
Generic savingsNot listedNot listed